Target Identification

Target Validation

Hit Identification

Hit-to-Lead

Lead Optimization

Pre-Clinical Studies

Clinical Development

INCUBATION PROJECTS
MATURATION PROJECTS
  • Novel MLL-AF9 AML biomarkers & Antibodies
  • Pharmacological Chaperones *
  • Drug repositioning in AML
  • Mature Cell Expansion
  • Undisclosed Project 5
  • Undisclosed Project 6
  • Undisclosed Project 4
  • Stem Cell expansion & Transplantation (Small molecules)
  • Undisclosed Project 7
  • Ribavirin in Leukemia
  • Immunotherapy in Leukemia

For more information,
View this document

 
Enabling Drug Discovery Tools
  • CRISPR/Cas9 chemogenomic profiling
  • Novel approach for target ID
  • BRET Biosensor Program
  • Cyclic peptidomimetics
  • Proprietary Small Molecules (IRIC’s collection)
  • SUMOylation Detection Method

Legend

  *    Project for potential partnership
  IRICoR investment at later stage (Maturation Project Committee)
  IRICoR investment at early stage (Incubation Project Committee)
  IRICoR investment at both early and late stages of development

Last update: 2017-10-10