Target Identification

Target Validation

Hit Identification

Hit-to-Lead

Lead Optimization

Pre-Clinical Studies

Clinical Development

INCUBATION PROJECTS
MATURATION PROJECTS
  • Undisclosed Project 2
  • Novel ILK modulators
  • Small molecule inhibitors of the MAP kinases signaling pathway
  • Novel fragments in AML resistance *
  • HDACs as antifungals
  • Human Telomerase Inhibitors
  • Undisclosed Project 4
  • Undisclosed Project 3
  • Plk1-specific inhibitors
  • Inhibition of GPCR in brain tumors *
  • Undisclosed Project 5
  • Pharmacological Chaperones *
  • Chemogenomics in AML *
  • Stem Cell expansion & Transplantation (Small molecules) *
  • Ribavirin in Leukemia
  • Undisclosed Project 6

For more information,
View this document

 
Enabling Drug Discovery Tools
  • Engineered Kinases
  • CRISPR/Cas9 chemogenomic profiling
  • BRET Biosensor Program
  • Cyclic peptidomimetics
  • Proprietary Small Molecules (IRIC’s collection)
  • SUMOylation Detection Method

Legend

  *    Project for potential partnership
  IRICoR investment at later stage (Maturation Project Committee)
  IRICoR investment at early stage (Incubation Project Committee)
  IRICoR investment at both early and late stages of development

Last update: 2017-08-25